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   Table of Contents - Current issue
October-December 2021
Volume 8 | Issue 4
Page Nos. 133-176

Online since Wednesday, August 17, 2022

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Quantitative analysis of diffusion-weighted imaging and signal-to-noise ratio on the efficacy of albendazole liposome in the treatment of cerebral alveolar echinococcosis p. 133
Hui Xing, Xiaodan Du, Nuerbiyemu Abulikemu, Jing Yang, Xin Gao, Jundi Liu, Chunhui Jiang, Jingwen Li, Jian Wang
OBJECTIVE: To investigate the feasibility of diffusion-weighted imaging (DWI) and signal-to-noise ratio (SNR) of lesions in evaluating the efficacy of albendazole liposomes in the treatment of cerebral alveolar echinococcosis (CAE). MATERIALS AND METHODS: Sixteen patients with CAE who met the inclusion criteria from April 2017 to December 2020 were enrolled. All patients underwent routine magnetic resonance sequence examination and DWI examination. The b-value were 1000 s/mm2 and 3000 s/mm2. The apparent diffusion coefficient (ADC) value and SNR of lesions before and after treatment were compared. The data of each group were statistically analyzed by Wilcoxon signed-rank sum test. RESULTS: After 1 year of treatment with albendazole liposomes, the SNR of lesions on T2WI sequence increased. There was a significant difference between the SNR of the same lesion before and after follow-up (P < 0.05). The ADC values of lesion parenchyma and edema area before and after treatment were compared. The difference between them was statistically significant in the both b values (ADC of parenchyma, P < 0.05; ADC of edema area, P < 0.001). Through binary linear classification, it was found that under the same b value, the effect of drugs on the edema area was more obvious than that on the parenchyma area; under different b values, the higher the b value, the higher the ability to evaluate the curative effect of drug therapy. CONCLUSION: Albendazole liposome is effective in the treatment of CAE, and long-term imaging follow-up of patients with CAE treated with albendazole liposome is necessary. When the change in conventional images is inapparent, the quantitative analysis of ADC value and SNR of lesions on T2WI can provide an objective basis for the evaluation of the curative effect of drug treatment in CAE.
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Impact of fatty liver on acute pancreatitis severity and prognosis: A meta-analysis of English and Chinese studies p. 140
Mingkuan Jiang, Miao Zhang, Lirong Zhang, Lin Luo, Qiang Chen
BACKGROUND: Previous studies showed a significant correlation between fatty liver (FL) and acute pancreatitis (AP) onset, but the impact of FL on AP severity and prognosis remains uncertain. Therefore, we systematically searched existing publications in English and Chinese and conducted a meta-analysis to evaluate the effect of FL on AP severity and prognosis. OBJECTIVE: The purpose of this study was to analyze the correlation between FL and AP severity and prognosis. MATERIALS AND METHODS: All published controlled clinical studies on the relationship between FL and AP were identified by searching available electronic databases. We assessed the impact of FL disease on AP biochemical indicators, severity, and prognosis using pooled individual studies with an odds ratio (OR), standardized mean difference, and weighted mean difference. RESULTS: Thirteen clinical case − control studies met the meta-analysis entry criteria, and these studies included 6570 patients; among them, 2110 were patients with FL-relatedAP (FLAP) and 4460 were patients with non-FL-related AP (NFLAP). The meta-analysis results showed that the percentage of mild AP in FLAP was lower than that in NFLAP (OR = 0.32, P < 0.001), but the percentage of moderately severe AP (MSAP) and severe AP (SAP) in FLAP was higher than that in NFLAP (OR = 2.66 and 2.57, respectively, P < 0.001). The various prognostic indicators included the acute physiology and chronic health evaluation II score, systemic complications, local complications, total length of hospital stay, and mortality, which were all significantly higher in FLAP than in NFLAP (P < 0.05 for all). CONCLUSION: AP severity and prognosis were different between FLAP and NFLAP patients, and FL could be used as an independent risk factor for MSAP and SAP.
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Clinical and imaging manifestations of pediatric melioidosis in Hainan, China p. 150
Long Fan, Yehua Wu, Shengshi Mai, Hong Lu, Yuefu Zhan
OBJECTIVE: The objective of this study was to investigate the clinical and imaging manifestations of melioidosis in children in Hainan Province, China, to improve its understanding. MATERIALS AND METHODS: We retrospectively analyzed 10 children with melioidosis in Hainan Province, China, from January 2002 to November 2021. We collected clinical and imaging data. These data were analyzed retrospectively by two radiologists with more than 10 years' radiology imaging experience. RESULTS: The patients' average age was 8.4 years (range: 17 days to 15 years), the male-to-female ratio was 6:4, and the average length of hospital stay was 31.5 days (5–96 days). Only two patients had underlying diseases, which were acute lymphocytic leukocyte hepatitis and hepatitis B. One patient had no onset of fever, and the other nine patients had a fever, with an average temperature of 39.5°C (38.4–40.3°C). Two patients had a low white blood cell count (0.27 × 109/L, 3.6 × 109/L), four had a normal white blood cell count, and two had a slightly high white blood cell count (13.6 × 109/L, 14.2 × 109/L). Two patients aged <1 year had a high white blood cell count >34 × 109/L and died. One patient was automatically discharged from the hospital and stopped treatment because of economic factors, and the rest improved after treatment. The neutrophil count was normal in two patients, but it was increased in the other patients. There were no data of C-reactive protein (CRP) measurements in three patients, and four of the other seven patients showed greatly elevated CRP concentrations. Among these four patients, two died and two were cured. One patient had sepsis, three had septicopyemia, and two had multiple organ dysfunction syndrome; among these six patients, one died and others improved. Four patients with pneumonia showed scattered exudation, consolidation, and nodules in both lungs, which developed into lung abscesses, as well as melioidosis and mumps. Three patients showed parotid swelling and abscess formation multilocular. One patient had liver and splenic abscesses. One patient had neck abscesses and one had perineal skin abscesses. One patient had purulent meningitis (clinical diagnosis) and disseminated intravascular coagulation (DIC), and this patient died. CONCLUSIONS: For patients in endemic areas, and those who have clinical manifestations of sepsis, pneumonia, mumps, and liver and splenic abscesses on imaging manifestations, the possibility of melioidosis should be considered. Microbial culture should be carried out as soon as possible, and these results of culture should be considered. Antibiotic treatment should be performed before a diagnosis. Mortality is more likely in patients who are aged <1 year and have considerably elevated CRP concentrations, multiple organ dysfunction syndrome, and central nervous system infection/DIC.
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Manual severity evaluation methods for novel coronavirus pneumonia based on computed tomography imaging p. 158
Qiang Chen, Lin Luo
Computed tomography (CT) examination plays an indispensable role in the diagnosis of coronavirus disease-2019 (COVID-19). Many studies have evaluated the severity of COVID-19 based on CT images, with the severity of COVID-19 being evaluated either manually or by using artificial intelligence. In this review, the recently reported methods for manually evaluating COVID-19 severity based on CT images are summarized and divided into three categories: evaluation based on the extent of abnormalities; evaluation based on the characteristics of abnormalities; and evaluation based on both the extent and characteristics of abnormalities.
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Comparative study on the diagnostic value of chest X-ray and computed tomography in patients with COVID- 19 p. 168
Lingbo Deng, Yi Zhu, Wen Zhou, Guanxun Cheng
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Rare imaging-based diagnosis of pulmonary schistosomiasis: A case report p. 170
Xiao Chen, Qiuyuan Yang, Haijun He, Ping Zhang, Wenshuai Duan, Tengfei Ke, Bin Yang
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Reduction of door-to-chest computed tomographic time in a fever clinic following anti-COVID-19 efforts p. 174
Yu Yang, Minggui Lin, Weiwei Wu
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